首页> 外文OA文献 >The 100% Rapid Rescreening Is Efficient In The Detection Of False-negative Results And Varies According To The Quality Of The Sample: A Brazilian Experience [a Revisão Rápida De 100% é Eficiente Na Detecção De Resultados Falsos-negativos Dos Exames Citopatológicos Cervicais E Varia Com A Adequabilidade Da Amostra: Uma Experiência No Brasil]
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The 100% Rapid Rescreening Is Efficient In The Detection Of False-negative Results And Varies According To The Quality Of The Sample: A Brazilian Experience [a Revisão Rápida De 100% é Eficiente Na Detecção De Resultados Falsos-negativos Dos Exames Citopatológicos Cervicais E Varia Com A Adequabilidade Da Amostra: Uma Experiência No Brasil]

机译:100%快速重新筛查可有效检测假阴性结果,并根据样品质量而有所不同:巴西的经验样品的适用性:巴西的经验]

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摘要

PURPOSE: to evaluate the efficiency of the 100% rapid rescreening in the detection of false-negative results and to verify whether the results vary according to the adequacy of the sample and the woman's age group. METHODS: to evaluate the efficiency of the rapid rescreening, the 5,530 smears classified as negative by the routine screening, after being submitted to the rapid rescreening of 100%, were compared with the rescreening of the smears on the basis of clinical criteria and 10% random rescreening. For statistical analysis, the variables were evaluated descriptively and the χ2 test and the Cochran-Armitage test were applied to compare results. RESULTS: of the 141 smears identified as suspicious according to the rapid rescreening method, 84 (59.6%) cases were confirmed in the final diagnosis, of which 36 (25.5%) were classified as atypical squamous cells of undetermined significance, five (3.5%) as atypical squamous cells that cannot exclude high-grade squamous intraepithelial lesion, 34 (24.1%) as low-grade squamous intraepithelial lesion, six (4.3%) as high-grade squamous intraepithelial lesion, and three (2.1%) as atypical glandular cells. Of the 84 suspect smears confirmed in the final diagnosis, 62 (73.8%) smears were classified as adequate and 22 (26.2%) as adequate but with some limitation, but no significant difference was observed with the woman's age. CONCLUSIONS: the results of this study show that rapid rescreening is an efficient option for internal quality control for the detection of false-negative cervical smear results. In addition, it should be noted that rapid rescreening performed better when the sample was classified as adequate for analysis; however, it did not vary according to the woman's age group.
机译:目的:评估在假阴性结果检测中进行100%快速重新筛查的效率,并验证结果是否根据样品和女性年龄段的不同而有所不同。方法:为评估快速筛查的效率,将常规筛查归为阴性的5,530例涂片在进行100%的快速筛查后,与根据临床标准和10%的涂片再筛进行比较随机重新筛选。为了进行统计分析,对变量进行描述性评估,并应用χ2检验和Cochran-Armitage检验比较结果。结果:根据快速重新筛查方法鉴定出的141例涂片可疑,最终诊断中确诊84例(59.6%),其中36例(25.5%)被归为具有不确定性的非典型鳞状细胞,五例(3.5%) )是不能排除高度鳞状上皮内病变的非典型鳞状细胞,34个(24.1%)为低度鳞状上皮内病变,六个(4.3%)为高度鳞状上皮内病变和三个(2.1%)为非典型腺体细胞。在最终诊断中确认的84个可疑涂片中,有62个(73.8%)涂片被分类为适当,22个(26.2%)涂片被分类为适当,但有一定限制,但是与该妇女的年龄没有显着差异。结论:这项研究的结果表明,快速重新筛查是用于检测假阴性宫颈涂片结果的内部质量控制的有效选择。另外,应该注意的是,当样品被归类为足以进行分析时,快速重新筛选的效果更好。但是,这并没有根据女性的年龄段而有所不同。

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